Early on instructors identify issues with students. Some have problems articulating or completing assignments. I find it is important to connect with the student and provide advice on how to improve. I find in the first week of forums and assignments, I can identify these issues. It is best to address short comings right away.

I find that I when I answer an email from a student quickly, it makes the student feel comfortable. I also send personal emails through out the semester simply asking how they are doing and provide them with an assessment early on. It takes some work, but it does help with the issue of virtual versus the traditional classroom.